First Flight Biosciences provides services to our clients for their hit identification and hit-to-lead programs. We undertake assay development in major target classes, such as GPCRs, kinases, ion channels and transporters, and in a high-throughput screening format using plate-based platforms. Our screening capabilities span from cell line generation, biochemical, and cell-based functional assays for receptors, enzymes and ion channels in a variety of techniques, including:

Fluorescence (e.g. HTRF, FP, FRET, FLIPR, Flexstation)

Absorbance

Luminescence (e.g. luciferase, b-lactamase, deGFP, reporter gene) Radiometrics (e.g. SPA, MicroBeta, Filtration)

Electrophysiology (e.g. patch clamps)

ImageXpress (e.g. live cell image HCA/HCS)